TY  - GEN
AU  - De Ravin,Suk See
AU  - Cowen,Edward W
AU  - Zarember,Kol A
AU  - Whiting-Theobald,Narda L
AU  - Kuhns,Douglas B
AU  - Sandler,Netanya G
AU  - Douek,Daniel C
AU  - Pittaluga,Stefania
AU  - Poliani,Pietro L
AU  - Lee,Yu Nee
AU  - Notarangelo,Luigi D
AU  - Wang,Lei
AU  - Alt,Frederick W
AU  - Kang,Elizabeth M
AU  - Milner,Joshua D
AU  - Niemela,Julie E
AU  - Fontana-Penn,Mary
AU  - Sinal,Sara H
AU  - Malech,Harry L
TI  - Hypomorphic Rag mutations can cause destructive midline granulomatous disease
SN  - 1528-0020
PY  - 2010///0930
KW  - Adolescent
KW  - Animals
KW  - Cells, Cultured
KW  - Forkhead Transcription Factors
KW  - Gene Rearrangement
KW  - Genes, Immunoglobulin
KW  - Granulomatous Disease, Chronic
KW  - etiology
KW  - Homeodomain Proteins
KW  - genetics
KW  - Humans
KW  - Immunoglobulin G
KW  - immunology
KW  - Immunophenotyping
KW  - Lymphocytes
KW  - Male
KW  - Mice
KW  - Mutation, Missense
KW  - Recombinases
KW  - metabolism
KW  - Severe Combined Immunodeficiency
KW  - T-Lymphocytes, Regulatory
KW  - Thymectomy
KW  - Transcription Factors
KW  - Transgenes
KW  - physiology
KW  - AIRE Protein
N1  - Publication Type: Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
UR  - https://doi.org/10.1182/blood-2010-02-267583
ER  -