Emmanouilidou, Evangelia <br/><br/>
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.  [electronic resource] 

 -  The Journal of neuroscience : the official journal of the Society for Neuroscience  May 2010 
 - 6838-51 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1529-2401 
<br/><br/><label>Standard No.: </label>10.1523/JNEUROSCI.5699-09.2010  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analysis of Variance<br/>Animals<br/>Brefeldin A--pharmacology<br/>Calcium--metabolism<br/>Cell Death--drug effects<br/>Cell Differentiation--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Cells, Cultured<br/>Cerebral Cortex--cytology<br/>Chromatography, High Pressure Liquid--methods<br/>Culture Media, Conditioned--chemistry<br/>Cytotoxicity Tests, Immunologic--methods<br/>Dose-Response Relationship, Drug<br/>Endocytosis--drug effects<br/>Exosomes--physiology<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Hydrogen Peroxide--pharmacology<br/>Immunoprecipitation--methods<br/>Mass Spectrometry--methods<br/>Microscopy, Confocal--methods<br/>Microscopy, Electron, Transmission--methods<br/>Molecular Weight<br/>Multivesicular Bodies--drug effects<br/>Nerve Tissue Proteins--metabolism<br/>Neuroblastoma--pathology<br/>Neurons--drug effects<br/>Peptides--pharmacology<br/>Piperidines--pharmacology<br/>Presenilin-1--pharmacology<br/>Protein Synthesis Inhibitors--pharmacology<br/>Pyrazoles--pharmacology<br/>Rats<br/>Receptors, Transferrin--metabolism<br/>Serum--metabolism<br/>Subcellular Fractions--drug effects<br/>Temperature<br/>Transfection<br/>alpha-Synuclein--genetics<br/>beta-Galactosidase--genetics