TY  - GEN
AU  - Feldmann,Georg
AU  - Mishra,Anjali
AU  - Hong,Seung-Mo
AU  - Bisht,Savita
AU  - Strock,Christopher J
AU  - Ball,Douglas W
AU  - Goggins,Michael
AU  - Maitra,Anirban
AU  - Nelkin,Barry D
TI  - Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling
SN  - 1538-7445
PY  - 2010///0617
KW  - Adaptor Proteins, Signal Transducing
KW  - biosynthesis
KW  - Animals
KW  - Cell Cycle Proteins
KW  - Cell Growth Processes
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cyclin-Dependent Kinase 5
KW  - antagonists & inhibitors
KW  - Down-Regulation
KW  - Gene Knockdown Techniques
KW  - Humans
KW  - MAP Kinase Signaling System
KW  - Mice
KW  - Pancreatic Neoplasms
KW  - enzymology
KW  - Phosphatidylinositol 3-Kinases
KW  - metabolism
KW  - Proto-Oncogene Proteins c-akt
KW  - Signal Transduction
KW  - Xenograft Model Antitumor Assays
KW  - ral GTP-Binding Proteins
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/0008-5472.CAN-09-1107
ER  -