TY - GEN AU - Dang,Chau AU - Lin,Nancy AU - Moy,Beverly AU - Come,Steven AU - Sugarman,Steven AU - Morris,Patrick AU - Abbruzzi,Alyson AU - Chen,Carol AU - Steingart,Richard AU - Patil,Sujata AU - Norton,Larry AU - Winer,Eric AU - Hudis,Clifford TI - Dose-dense doxorubicin and cyclophosphamide followed by weekly paclitaxel with trastuzumab and lapatinib in HER2/neu-overexpressed/amplified breast cancer is not feasible because of excessive diarrhea SN - 1527-7755 PY - 2010///0706 KW - Adult KW - Aged KW - Antibodies, Monoclonal KW - administration & dosage KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Combined Chemotherapy Protocols KW - adverse effects KW - Breast Neoplasms KW - drug therapy KW - Cyclophosphamide KW - Diarrhea KW - chemically induced KW - Dose-Response Relationship, Drug KW - Doxorubicin KW - Feasibility Studies KW - Female KW - Filgrastim KW - Follow-Up Studies KW - Gene Amplification KW - Granulocyte Colony-Stimulating Factor KW - Humans KW - Immunoenzyme Techniques KW - In Situ Hybridization, Fluorescence KW - Lapatinib KW - Middle Aged KW - Neoplasm Recurrence, Local KW - Neoplasm Staging KW - Paclitaxel KW - Pilot Projects KW - Polyethylene Glycols KW - Quinazolines KW - Receptor, ErbB-2 KW - genetics KW - Recombinant Proteins KW - Survival Rate KW - Trastuzumab KW - Treatment Outcome N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1200/JCO.2009.26.5900 ER -