Tong, Youren <br/><br/>
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  May 2010 
 - 9879-84 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1004676107  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aging<br/>Animals<br/>Apoptosis<br/>Autophagy<br/>Dopamine--metabolism<br/>Homeostasis<br/>Kidney Diseases--genetics<br/>Leucine-Rich Repeat Serine-Threonine Protein Kinase-2<br/>Lysosomes--metabolism<br/>Mice<br/>Mice, Knockout<br/>Oxidation-Reduction<br/>Protein Serine-Threonine Kinases--deficiency<br/>Ubiquitination<br/>alpha-Synuclein--metabolism