Ning, Yanxia <br/><br/>
IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.  [electronic resource] 

 -  Molecular cancer therapeutics  May 2010 
 - 1274-85 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1538-8514 
<br/><br/><label>Standard No.: </label>10.1158/1535-7163.MCT-09-1169  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Breast Neoplasms--drug therapy<br/>Carcinoma--drug therapy<br/>Caspases--metabolism<br/>Drug Evaluation, Preclinical<br/>Drug Resistance, Neoplasm--drug effects<br/>Drug Synergism<br/>Estradiol--analogs & derivatives<br/>Female<br/>Fulvestrant<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Interferon Regulatory Factor-1--genetics<br/>Interferon-gamma--pharmacology<br/>NF-kappa B--genetics<br/>Proto-Oncogene Proteins c-bcl-2--genetics<br/>STAT1 Transcription Factor--genetics<br/>Signal Transduction--drug effects<br/>Tumor Cells, Cultured