Jacobson, Ingemar

Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit. [electronic resource] - Journal of pharmacological and toxicological methods - 40-6 p. digital

Publication Type: Journal Article

1873-488X

10.1016/j.vascn.2010.04.010 doi


Animals
Anti-Arrhythmia Agents--pharmacology
Arrhythmias, Cardiac--chemically induced
Cell Line
ERG1 Potassium Channel
Electrocardiography
Embryo, Mammalian
Ether-A-Go-Go Potassium Channels--metabolism
Heart--drug effects
Humans
Ion Channels--antagonists & inhibitors
Kidney
Long QT Syndrome--chemically induced
Male
Methoxamine--pharmacology
Models, Statistical
Phenethylamines--pharmacology
Rabbits
Rats
Sulfonamides--pharmacology
Torsades de Pointes--chemically induced