TY  - GEN
AU  - Oeseburg,Hisko
AU  - de Boer,Rudolf A
AU  - Buikema,Hendrik
AU  - van der Harst,Pim
AU  - van Gilst,Wiek H
AU  - Silljé,Herman H W
TI  - Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A
SN  - 1524-4636
PY  - 2010///0712
KW  - Adamantane
KW  - analogs & derivatives
KW  - Animals
KW  - Cells, Cultured
KW  - Cellular Senescence
KW  - drug effects
KW  - Cyclic AMP
KW  - metabolism
KW  - Cyclic AMP Response Element-Binding Protein
KW  - Cyclic AMP-Dependent Protein Kinases
KW  - DNA Damage
KW  - Diabetes Mellitus
KW  - drug therapy
KW  - Dipeptidyl-Peptidase IV Inhibitors
KW  - pharmacology
KW  - Disease Models, Animal
KW  - Dose-Response Relationship, Drug
KW  - Endothelial Cells
KW  - Enzyme Activation
KW  - Exenatide
KW  - Glucagon-Like Peptide 1
KW  - Glucagon-Like Peptide-1 Receptor
KW  - Heme Oxygenase-1
KW  - Humans
KW  - Hydrogen Peroxide
KW  - Hypoglycemic Agents
KW  - Male
KW  - NAD(P)H Dehydrogenase (Quinone)
KW  - Nitriles
KW  - Oxidants
KW  - Oxidative Stress
KW  - Peptides
KW  - Phosphatidylinositol 3-Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - Pyrrolidines
KW  - Rats
KW  - Rats, Zucker
KW  - Reactive Oxygen Species
KW  - Receptors, Glucagon
KW  - Signal Transduction
KW  - Venoms
KW  - Vildagliptin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1161/ATVBAHA.110.206425
ER  -