TY - GEN AU - Pechloff,Konstanze AU - Holch,Julian AU - Ferch,Uta AU - Schweneker,Marc AU - Brunner,Kristina AU - Kremer,Markus AU - Sparwasser,Tim AU - Quintanilla-Martinez,Leticia AU - Zimber-Strobl,Ursula AU - Streubel,Berthold AU - Gewies,Andreas AU - Peschel,Christian AU - Ruland,Jürgen TI - The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma SN - 1540-9538 PY - 2010///0608 KW - Animals KW - Antigens, CD KW - genetics KW - Antigens, Differentiation, T-Lymphocyte KW - Chromosomes, Human, Pair 5 KW - Chromosomes, Human, Pair 9 KW - Disease Models, Animal KW - Embryonic Stem Cells KW - physiology KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Interleukin-2 KW - Intracellular Signaling Peptides and Proteins KW - Lectins, C-Type KW - Lymphoma, T-Cell, Peripheral KW - Lymphoproliferative Disorders KW - Mice KW - Protein-Tyrosine Kinases KW - Receptors, Antigen, T-Cell KW - Recombinant Fusion Proteins KW - metabolism KW - Signal Transduction KW - Spleen KW - enzymology KW - Syk Kinase KW - Translocation, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.20092042 ER -