TY - GEN AU - Papp-Wallace,Krisztina M AU - Taracila,Magdalena AU - Hornick,John M AU - Hujer,Andrea M AU - Hujer,Kristine M AU - Distler,Anne M AU - Endimiani,Andrea AU - Bonomo,Robert A TI - Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase SN - 1098-6596 PY - 2010///0921 KW - Bacterial Proteins KW - metabolism KW - Cephalosporinase KW - Clavulanic Acid KW - pharmacology KW - Computer Simulation KW - Enzyme Inhibitors KW - chemistry KW - Hydrogen Bonding KW - Kinetics KW - Microbial Sensitivity Tests KW - Molecular Structure KW - Mutagenesis, Site-Directed KW - Penicillanic Acid KW - analogs & derivatives KW - Protein Structure, Secondary KW - Spectrometry, Mass, Electrospray Ionization KW - Substrate Specificity KW - Sulbactam KW - Tazobactam KW - beta-Lactamase Inhibitors KW - beta-Lactamases KW - beta-Lactams N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1128/AAC.00197-10 ER -