TY - GEN AU - Watanabe,Naoto AU - Image Image,Image Image AU - Takagi,Shizuka AU - Image Image,Image Image AU - Tominaga,Aya AU - Image Image,Image AU - Tomita,Taisuke AU - Image Image,Image Image AU - Iwatsubo,Takeshi AU - Image Image,Image TI - Functional analysis of the transmembrane domains of presenilin 1: participation of transmembrane domains 2 and 6 in the formation of initial substrate-binding site of gamma-secretase SN - 1083-351X PY - 2010///0824 KW - Amino Acid Sequence KW - Amyloid Precursor Protein Secretases KW - genetics KW - Aspartic Acid Endopeptidases KW - Binding Sites KW - Cell Line KW - Genetic Complementation Test KW - Genetic Vectors KW - Humans KW - Immunoblotting KW - Molecular Sequence Data KW - Mutation KW - Photoaffinity Labels KW - Presenilin-1 KW - Retroviridae KW - Substrate Specificity KW - Transduction, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.M110.101287 ER -