Gnoth, M J <br/><br/>
In vitro to in vivo comparison of the substrate characteristics of sorafenib tosylate toward P-glycoprotein.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Aug 2010 
 - 1341-6 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.110.032052  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism<br/>Animals<br/>Anti-Arrhythmia Agents--metabolism<br/>Benzenesulfonates--blood<br/>Brain--metabolism<br/>Caco-2 Cells<br/>Digoxin--metabolism<br/>Humans<br/>LLC-PK1 Cells<br/>Male<br/>Mice<br/>Mice, Knockout<br/>Niacinamide--analogs & derivatives<br/>Permeability<br/>Phenylurea Compounds<br/>Protein Kinase Inhibitors--blood<br/>Pyridines--blood<br/>Sorafenib<br/>Swine