TY - GEN AU - Søndergaard,Jonas N AU - Nazarian,Ramin AU - Wang,Qi AU - Guo,Deliang AU - Hsueh,Teli AU - Mok,Stephen AU - Sazegar,Hooman AU - MacConaill,Laura E AU - Barretina,Jordi G AU - Kehoe,Sarah M AU - Attar,Narsis AU - von Euw,Erika AU - Zuckerman,Jonathan E AU - Chmielowski,Bartosz AU - Comin-Anduix,Begoña AU - Koya,Richard C AU - Mischel,Paul S AU - Lo,Roger S AU - Ribas,Antoni TI - Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032 SN - 1479-5876 PY - 2010///0803 KW - Amino Acid Substitution KW - genetics KW - Animals KW - Apoptosis KW - drug effects KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Survival KW - Diagnostic Imaging KW - Drug Resistance, Neoplasm KW - Genome, Human KW - Humans KW - Indoles KW - pharmacology KW - MAP Kinase Signaling System KW - Melanoma KW - enzymology KW - Mice KW - Mutation KW - Phosphatidylinositol 3-Kinases KW - metabolism KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins B-raf KW - antagonists & inhibitors KW - Proto-Oncogene Proteins c-akt KW - Sulfonamides KW - Vemurafenib KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/1479-5876-8-39 ER -