Søndergaard, Jonas N <br/><br/>
Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.  [electronic resource] 

 -  Journal of translational medicine  Apr 2010 
 - 39 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1479-5876 
<br/><br/><label>Standard No.: </label>10.1186/1479-5876-8-39  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Substitution--genetics<br/>Animals<br/>Apoptosis--drug effects<br/>Cell Cycle--drug effects<br/>Cell Line, Tumor<br/>Cell Survival--drug effects<br/>Diagnostic Imaging<br/>Drug Resistance, Neoplasm--drug effects<br/>Genome, Human--genetics<br/>Humans<br/>Indoles--pharmacology<br/>MAP Kinase Signaling System--drug effects<br/>Melanoma--enzymology<br/>Mice<br/>Mutation--genetics<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphorylation--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>Sulfonamides--pharmacology<br/>Vemurafenib<br/>Xenograft Model Antitumor Assays