Long, Jianting <br/><br/>
Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia.  [electronic resource] 

 -  Blood  Jul 2010 
 - 71-80 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1528-0020 
<br/><br/><label>Standard No.: </label>10.1182/blood-2010-01-261628  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Disease<br/>Adult<br/>Aged<br/>Aged, 80 and over<br/>Apoptosis--drug effects<br/>Cell Cycle Proteins<br/>Cell Line, Tumor<br/>Cells, Cultured<br/>Drug Resistance, Neoplasm--drug effects<br/>Female<br/>Flow Cytometry<br/>Humans<br/>Imidazoles--pharmacology<br/>Immunoblotting<br/>Indoles--pharmacology<br/>Leukemia, Myeloid--genetics<br/>Male<br/>Middle Aged<br/>Nuclear Proteins--genetics<br/>Piperazines--pharmacology<br/>Proto-Oncogene Proteins--genetics<br/>Proto-Oncogene Proteins c-mdm2--antagonists & inhibitors<br/>Reverse Transcriptase Polymerase Chain Reaction<br/>Spiro Compounds--pharmacology<br/>Tumor Cells, Cultured<br/>Tumor Suppressor Protein p53--genetics<br/>Young Adult<br/>fms-Like Tyrosine Kinase 3--genetics