TY - GEN AU - Ross,Jillian AU - Plummer,Simon M AU - Rode,Anja AU - Scheer,Nico AU - Bower,Conrad C AU - Vogel,Ortwin AU - Henderson,Colin J AU - Wolf,C Roland AU - Elcombe,Clifford R TI - Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo SN - 1096-0929 PY - 2010///1028 KW - Animals KW - Aryl Hydrocarbon Hydroxylases KW - biosynthesis KW - Cell Proliferation KW - drug effects KW - Chlordan KW - toxicity KW - Constitutive Androstane Receptor KW - Cytochrome P-450 CYP3A KW - Cytochrome P450 Family 2 KW - Humans KW - Hyperplasia KW - Hypertrophy KW - Liver KW - Liver Neoplasms, Experimental KW - chemically induced KW - Membrane Proteins KW - Mice KW - Mice, Inbred C57BL KW - Phenobarbital KW - Pregnane X Receptor KW - Receptors, Cytoplasmic and Nuclear KW - physiology KW - Receptors, Steroid KW - Species Specificity KW - Steroid Hydroxylases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/toxsci/kfq118 ER -