Yoshino, Hitoshi <br/><br/>
Structure-activity relationships of bioisosteric replacement of the carboxylic acid in novel androgen receptor pure antagonists.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  May 2010 
 - 3159-68 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2010.03.036  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Androgen Antagonists--chemical synthesis<br/>Animals<br/>Antineoplastic Agents, Hormonal--chemical synthesis<br/>Carboxylic Acids--chemical synthesis<br/>Cell Line, Tumor<br/>Dose-Response Relationship, Drug<br/>Inhibitory Concentration 50<br/>Male<br/>Mice<br/>Mice, SCID<br/>Molecular Structure<br/>Nitriles--chemical synthesis<br/>Prostatic Neoplasms--drug therapy<br/>Sulfonamides--chemical synthesis<br/>Thiohydantoins--chemical synthesis<br/>Xenograft Model Antitumor Assays