TY - GEN AU - Gringhuis,Sonja I AU - van der Vlist,Michiel AU - van den Berg,Linda M AU - den Dunnen,Jeroen AU - Litjens,Manja AU - Geijtenbeek,Teunis B H TI - HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells SN - 1529-2916 PY - 2010///0817 KW - Cell Adhesion Molecules KW - immunology KW - Cells, Cultured KW - Dendritic Cells KW - HIV Envelope Protein gp120 KW - genetics KW - HIV Infections KW - HIV-1 KW - pathogenicity KW - Humans KW - Immunity, Innate KW - Lectins, C-Type KW - NF-kappa B KW - Phosphorylation KW - Positive Transcriptional Elongation Factor B KW - metabolism KW - Protein Binding KW - Protein Engineering KW - Proto-Oncogene Proteins c-raf KW - RNA Polymerase II KW - Receptors, Cell Surface KW - Second Messenger Systems KW - Sequence Deletion KW - Toll-Like Receptor 8 KW - Transcriptional Activation KW - Virus Replication KW - drug effects N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ni.1858 ER -