TY  - GEN
AU  - Tsukada,Tomoharu
AU  - Tamaki,Kazuhiko
AU  - Tanaka,Jun
AU  - Takagi,Toshiyuki
AU  - Yoshida,Taishi
AU  - Okuno,Akira
AU  - Shiiki,Takeshi
AU  - Takahashi,Mizuki
AU  - Nishi,Takahide
TI  - A prodrug approach towards the development of tricyclic-based FBPase inhibitors
SN  - 1464-3405
PY  - 2010///0727
KW  - Alanine
KW  - analogs & derivatives
KW  - Animals
KW  - Cells, Cultured
KW  - Crystallography, X-Ray
KW  - Cytochrome P-450 CYP3A
KW  - metabolism
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Haplorhini
KW  - Molecular Conformation
KW  - Organophosphonates
KW  - Prodrugs
KW  - Pyridines
KW  - chemistry
KW  - Structure-Activity Relationship
KW  - Thiazoles
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bmcl.2010.03.017
ER  -