LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo. [electronic resource]
- American journal of physiology. Endocrinology and metabolism Jun 2010
- E1261-73 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1522-1555
10.1152/ajpendo.00100.2010 doi
AMP-Activated Protein Kinases--metabolism Animals Blotting, Western Body Weight--physiology Diabetes Mellitus, Type 2--enzymology Eating--physiology Glucose Tolerance Test Insulin--blood Insulin Secretion Insulin-Secreting Cells--enzymology Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Microscopy, Fluorescence Protein Serine-Threonine Kinases--deficiency RNA Receptor-Interacting Protein Serine-Threonine Kinase 2 Receptor-Interacting Protein Serine-Threonine Kinases--genetics Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Specific Pathogen-Free Organisms Transgenes