TY  - GEN
AU  - Ramana,Kota V
AU  - Tammali,Ravinder
AU  - Srivastava,Satish K
TI  - Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells
SN  - 1538-8514
PY  - 2010///0707
KW  - Aldehyde Reductase
KW  - antagonists & inhibitors
KW  - Animals
KW  - Benzothiazoles
KW  - pharmacology
KW  - Cell Cycle
KW  - drug effects
KW  - Cell Cycle Proteins
KW  - genetics
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Colonic Neoplasms
KW  - enzymology
KW  - DNA, Neoplasm
KW  - metabolism
KW  - E2F1 Transcription Factor
KW  - G1 Phase
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Imidazolidines
KW  - Intercellular Signaling Peptides and Proteins
KW  - Mice
KW  - Neoplasm Proteins
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphorylation
KW  - Phthalazines
KW  - Protein Binding
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA, Messenger
KW  - Retinoblastoma Protein
KW  - S Phase
KW  - Signal Transduction
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/1535-7163.MCT-09-0795
ER  -