TY - GEN AU - Baghdasaryan,Anna AU - Claudel,Thierry AU - Kosters,Astrid AU - Gumhold,Judith AU - Silbert,Dagmar AU - Thüringer,Andrea AU - Leski,Katharina AU - Fickert,Peter AU - Karpen,Saul J AU - Trauner,Michael TI - Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation SN - 1468-3288 PY - 2010///0427 KW - ATP Binding Cassette Transporter, Subfamily B KW - genetics KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - pharmacology KW - Bile KW - metabolism KW - Bile Acids and Salts KW - biosynthesis KW - Bile Ducts KW - drug effects KW - Cell Proliferation KW - Cells, Cultured KW - Cholangitis, Sclerosing KW - drug therapy KW - Curcumin KW - Drug Evaluation, Preclinical KW - methods KW - Epithelial Cells KW - Fibroblasts KW - Inflammation Mediators KW - Liver Cirrhosis, Experimental KW - Male KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - PPAR gamma KW - Signal Transduction KW - ATP-Binding Cassette Sub-Family B Member 4 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/gut.2009.186528 ER -