Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation. [electronic resource]
- Gut Apr 2010
- 521-30 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1468-3288
10.1136/gut.2009.186528 doi
ATP Binding Cassette Transporter, Subfamily B--genetics Animals Anti-Inflammatory Agents, Non-Steroidal--pharmacology Bile--metabolism Bile Acids and Salts--biosynthesis Bile Ducts--drug effects Cell Proliferation--drug effects Cells, Cultured Cholangitis, Sclerosing--drug therapy Curcumin--pharmacology Drug Evaluation, Preclinical--methods Epithelial Cells--drug effects Fibroblasts--drug effects Inflammation Mediators--metabolism Liver Cirrhosis, Experimental--drug therapy Male Mice Mice, Knockout Mitogen-Activated Protein Kinase 1--metabolism Mitogen-Activated Protein Kinase 3--metabolism PPAR gamma--metabolism Signal Transduction--drug effects ATP-Binding Cassette Sub-Family B Member 4