Tammali, Ravinder
Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle. [electronic resource]
- Endocrinology May 2010
- 2140-50 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1945-7170
10.1210/en.2010-0160 doi
Aldehyde Reductase--antagonists & inhibitors
Animals
Aorta--metabolism
Blotting, Western
Cell Cycle--drug effects
Cell Proliferation
Cell Survival--drug effects
Cells, Cultured
Cyclins--genetics
Diabetes Mellitus, Experimental--genetics
Dose-Response Relationship, Drug
E2F1 Transcription Factor--genetics
G1 Phase
Glucose--pharmacology
Imidazolidines--pharmacology
Male
Muscle, Smooth, Vascular--cytology
Phosphorylation--drug effects
RNA Interference
Rats
Rats, Sprague-Dawley
Retinoblastoma Protein--metabolism
Reverse Transcriptase Polymerase Chain Reaction
S Phase
Tumor Necrosis Factor-alpha--pharmacology