TY - GEN AU - Bursavich,Matthew G AU - Brooijmans,Natasja AU - Feldberg,Lawrence AU - Hollander,Irwin AU - Kim,Stephen AU - Lombardi,Sabrina AU - Park,Kaapjoo AU - Mallon,Robert AU - Gilbert,Adam M TI - Novel benzofuran-3-one indole inhibitors of PI3 kinase-alpha and the mammalian target of rapamycin: hit to lead studies SN - 1464-3405 PY - 2010///0812 KW - Benzofurans KW - chemistry KW - Cell Line, Tumor KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - antagonists & inhibitors KW - Models, Molecular KW - Phosphoinositide-3 Kinase Inhibitors KW - Protein Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Structure-Activity Relationship KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2010.02.082 ER -