TY  - GEN
AU  - Uchinoumi,Hitoshi
AU  - Yano,Masafumi
AU  - Suetomi,Takeshi
AU  - Ono,Makoto
AU  - Xu,Xiaojuan
AU  - Tateishi,Hiroki
AU  - Oda,Tetsuro
AU  - Okuda,Shinichi
AU  - Doi,Masahiro
AU  - Kobayashi,Shigeki
AU  - Yamamoto,Takeshi
AU  - Ikeda,Yasuhiro
AU  - Ohkusa,Tomoko
AU  - Ikemoto,Noriaki
AU  - Matsuzaki,Masunori
TI  - Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor
SN  - 1524-4571
PY  - 2010///0524
KW  - Animals
KW  - Caffeine
KW  - Calcium Signaling
KW  - genetics
KW  - Cells, Cultured
KW  - Cyclic AMP-Dependent Protein Kinases
KW  - metabolism
KW  - Disease Models, Animal
KW  - Epinephrine
KW  - Excitation Contraction Coupling
KW  - Genotype
KW  - Isoproterenol
KW  - Membrane Potentials
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Myocardial Contraction
KW  - Myocytes, Cardiac
KW  - Peptide Fragments
KW  - Phenotype
KW  - Phosphorylation
KW  - Physical Exertion
KW  - Point Mutation
KW  - Protein Conformation
KW  - Protein Structure, Tertiary
KW  - Ryanodine Receptor Calcium Release Channel
KW  - chemistry
KW  - Sarcoplasmic Reticulum
KW  - Structure-Activity Relationship
KW  - Tachycardia, Ventricular
KW  - chemically induced
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1161/CIRCRESAHA.109.209312
ER  -