TY - GEN AU - Ito,Takumi AU - Ando,Hideki AU - Suzuki,Takayuki AU - Ogura,Toshihiko AU - Hotta,Kentaro AU - Imamura,Yoshimasa AU - Yamaguchi,Yuki AU - Handa,Hiroshi TI - Identification of a primary target of thalidomide teratogenicity SN - 1095-9203 PY - 2010///0325 KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Carrier Proteins KW - metabolism KW - Chick Embryo KW - Cullin Proteins KW - DNA-Binding Proteins KW - Embryo, Nonmammalian KW - drug effects KW - Embryonic Development KW - Fibroblast Growth Factors KW - genetics KW - Forelimb KW - abnormalities KW - Gene Expression Regulation, Developmental KW - HeLa Cells KW - Humans KW - Mutant Proteins KW - Peptide Hydrolases KW - Teratogens KW - Thalidomide KW - Ubiquitin-Protein Ligases KW - antagonists & inhibitors KW - Ubiquitination KW - Zebrafish KW - embryology KW - Zebrafish Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.1177319 ER -