TY - GEN AU - Manea,Simona-Adriana AU - Manea,Adrian AU - Heltianu,Constantina TI - Inhibition of JAK/STAT signaling pathway prevents high-glucose-induced increase in endothelin-1 synthesis in human endothelial cells SN - 1432-0878 PY - 2010///0615 KW - Cells, Cultured KW - Diabetic Angiopathies KW - genetics KW - Endothelial Cells KW - cytology KW - Endothelin-1 KW - biosynthesis KW - Enzyme Inhibitors KW - pharmacology KW - Glucose KW - metabolism KW - Humans KW - Hyperglycemia KW - Janus Kinases KW - antagonists & inhibitors KW - Promoter Regions, Genetic KW - drug effects KW - RNA, Messenger KW - STAT Transcription Factors KW - STAT1 Transcription Factor KW - Signal Transduction KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00441-010-0936-1 ER -