Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice. [electronic resource]
- Digestive diseases and sciences Nov 2010
- 3086-94 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1573-2568
10.1007/s10620-010-1157-x doi
Animals Apoptosis--drug effects Atorvastatin Colonic Neoplasms--prevention & control Colonic Polyps--prevention & control DNA Fragmentation Disease Models, Animal Heptanoic Acids--pharmacology Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology Immunoblotting In Situ Nick-End Labeling Male Mice Mice, Inbred C57BL Mice, Inbred Strains Mice, Nude Pyrroles--pharmacology Tumor Cells, Cultured Xenograft Model Antitumor Assays