TY - GEN AU - Ago,Tetsuro AU - Kuroda,Junya AU - Pain,Jayashree AU - Fu,Cexiong AU - Li,Hong AU - Sadoshima,Junichi TI - Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes SN - 1524-4571 PY - 2010///0430 KW - Aconitate Hydratase KW - metabolism KW - Aging KW - Animals KW - Apoptosis KW - drug effects KW - Cardiomegaly KW - enzymology KW - Cell Proliferation KW - Cells, Cultured KW - Cysteine KW - Disease Models, Animal KW - Enzyme Inhibitors KW - pharmacology KW - Fibrosis KW - Genotype KW - Humans KW - Mice KW - Mice, Transgenic KW - Mitochondria, Heart KW - Myocytes, Cardiac KW - NADH Dehydrogenase KW - NADPH Oxidase 4 KW - NADPH Oxidases KW - antagonists & inhibitors KW - Onium Compounds KW - Oxidation-Reduction KW - Oxidative Stress KW - Phenotype KW - Rats KW - Rats, Wistar KW - Rotenone KW - Superoxides KW - Transfection KW - Uncoupling Agents KW - Up-Regulation KW - Ventricular Dysfunction, Left KW - Ventricular Function, Left N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1161/CIRCRESAHA.109.213116 ER -