TY  - GEN
AU  - Banerji,Udai
AU  - Camidge,D Ross
AU  - Verheul,Henk M W
AU  - Agarwal,Roshan
AU  - Sarker,Debashis
AU  - Kaye,Stan B
AU  - Desar,Ingrid M E
AU  - Timmer-Bonte,Johanna N H
AU  - Eckhardt,S Gail
AU  - Lewis,Karl D
AU  - Brown,Kathryn H
AU  - Cantarini,Mireille V
AU  - Morris,Clive
AU  - George,Sarah M A
AU  - Smith,Paul D
AU  - van Herpen,Carla M L
TI  - The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer
SN  - 1557-3265
PY  - 2010///0520
KW  - Administration, Oral
KW  - Adult
KW  - Aged
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Benzimidazoles
KW  - Capsules
KW  - Female
KW  - Humans
KW  - MAP Kinase Kinase 1
KW  - antagonists & inhibitors
KW  - MAP Kinase Kinase 2
KW  - Male
KW  - Maximum Tolerated Dose
KW  - Middle Aged
KW  - Neoplasms
KW  - drug therapy
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/1078-0432.CCR-09-2483
ER  -