TY - GEN AU - Ghosh,Hiyaa Singhee AU - McBurney,Michael AU - Robbins,Paul D TI - SIRT1 negatively regulates the mammalian target of rapamycin SN - 1932-6203 PY - 2010///0930 KW - Animals KW - Antioxidants KW - pharmacology KW - Blotting, Western KW - Cell Line KW - Cells, Cultured KW - Fibroblasts KW - cytology KW - HeLa Cells KW - Humans KW - Immunoprecipitation KW - Intracellular Signaling Peptides and Proteins KW - metabolism KW - Jurkat Cells KW - Mice KW - Mice, Knockout KW - Models, Biological KW - Niacinamide KW - Protein Binding KW - Protein Serine-Threonine Kinases KW - RNA Interference KW - Resveratrol KW - Signal Transduction KW - drug effects KW - Sirtuin 1 KW - genetics KW - Stilbenes KW - TOR Serine-Threonine Kinases KW - Tuberous Sclerosis Complex 2 Protein KW - Tumor Suppressor Proteins N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1371/journal.pone.0009199 ER -