TY - GEN AU - Pang,Xiufeng AU - Yi,Zhengfang AU - Zhang,Jing AU - Lu,Binbin AU - Sung,Bokyung AU - Qu,Weijing AU - Aggarwal,Bharat B AU - Liu,Mingyao TI - Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway SN - 1538-7445 PY - 2010///0408 KW - Angiogenesis Inhibitors KW - pharmacology KW - Animals KW - Apoptosis KW - drug effects KW - Cell Growth Processes KW - Cell Line, Tumor KW - Chemotaxis KW - Endothelial Cells KW - cytology KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - metabolism KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Neovascularization, Pathologic KW - drug therapy KW - Pentacyclic Triterpenes KW - Prostatic Neoplasms KW - blood supply KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Ribosomal Protein S6 Kinases, 70-kDa KW - Specific Pathogen-Free Organisms KW - TOR Serine-Threonine Kinases KW - Triterpenes KW - Vascular Endothelial Growth Factor A KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-09-3201 ER -