TY  - GEN
AU  - Pan,Yong
AU  - Shadel,Gerald S
TI  - Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density
SN  - 1945-4589
PY  - 2010///0716
KW  - Cell Proliferation
KW  - drug effects
KW  - Cell Survival
KW  - physiology
KW  - DNA-Directed RNA Polymerases
KW  - genetics
KW  - Down-Regulation
KW  - Electron Transport Chain Complex Proteins
KW  - Electron Transport Complex IV
KW  - Gene Deletion
KW  - Gene Expression
KW  - Longevity
KW  - Membrane Potential, Mitochondrial
KW  - Membrane Proteins
KW  - metabolism
KW  - Mitochondria
KW  - Mitochondrial Proteins
KW  - Oxidative Phosphorylation
KW  - Oxygen Consumption
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - Reactive Oxygen Species
KW  - Ribosomal Proteins
KW  - Saccharomyces cerevisiae
KW  - Saccharomyces cerevisiae Proteins
KW  - antagonists & inhibitors
KW  - Signal Transduction
KW  - Sirolimus
KW  - pharmacology
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.18632/aging.100016
ER  -