Pan, Yong <br/><br/>
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density.  [electronic resource] 

 -  Aging  Jan 2009 
 - 131-45 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1945-4589 
<br/><br/><label>Standard No.: </label>10.18632/aging.100016  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Proliferation--drug effects<br/>Cell Survival--physiology<br/>DNA-Directed RNA Polymerases--genetics<br/>Down-Regulation--genetics<br/>Electron Transport Chain Complex Proteins--genetics<br/>Electron Transport Complex IV--genetics<br/>Gene Deletion<br/>Gene Expression--genetics<br/>Longevity--physiology<br/>Membrane Potential, Mitochondrial--physiology<br/>Membrane Proteins--metabolism<br/>Mitochondria--drug effects<br/>Mitochondrial Proteins--genetics<br/>Oxidative Phosphorylation<br/>Oxygen Consumption--drug effects<br/>Phosphatidylinositol 3-Kinases--genetics<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Protein Serine-Threonine Kinases--genetics<br/>Reactive Oxygen Species--metabolism<br/>Ribosomal Proteins--metabolism<br/>Saccharomyces cerevisiae--drug effects<br/>Saccharomyces cerevisiae Proteins--antagonists & inhibitors<br/>Signal Transduction--physiology<br/>Sirolimus--pharmacology<br/>Up-Regulation--physiology