TY  - GEN
AU  - Dumond,J B
AU  - Vourvahis,M
AU  - Rezk,N L
AU  - Patterson,K B
AU  - Tien,H-C
AU  - White,N
AU  - Jennings,S H
AU  - Choi,S O
AU  - Li,J
AU  - Wagner,M J
AU  - La-Beck,N M
AU  - Drulak,M
AU  - Sabo,J P
AU  - Castles,M A
AU  - Macgregor,T R
AU  - Kashuba,A D M
TI  - A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir
SN  - 1532-6535
PY  - 2010///0603
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - drug effects
KW  - Adult
KW  - Anti-HIV Agents
KW  - pharmacology
KW  - Area Under Curve
KW  - Cytochrome P-450 Enzyme System
KW  - Drug Combinations
KW  - Drug Interactions
KW  - Enzyme Induction
KW  - Enzyme Inhibitors
KW  - Female
KW  - Genotype
KW  - HIV Protease Inhibitors
KW  - Humans
KW  - Intestinal Mucosa
KW  - metabolism
KW  - Liver
KW  - Male
KW  - Pharmaceutical Preparations
KW  - administration & dosage
KW  - Phenotype
KW  - Polymorphism, Single Nucleotide
KW  - Pyridines
KW  - Pyrones
KW  - Ritonavir
KW  - Sulfonamides
KW  - Young Adult
N1  - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/clpt.2009.253
ER  -