Dumond, J B

A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir. [electronic resource] - Clinical pharmacology and therapeutics Jun 2010 - 735-42 p. digital

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1532-6535

10.1038/clpt.2009.253 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--drug effects
Adult
Anti-HIV Agents--pharmacology
Area Under Curve
Cytochrome P-450 Enzyme System--drug effects
Drug Combinations
Drug Interactions
Enzyme Induction--drug effects
Enzyme Inhibitors--pharmacology
Female
Genotype
HIV Protease Inhibitors--pharmacology
Humans
Intestinal Mucosa--metabolism
Liver--metabolism
Male
Pharmaceutical Preparations--administration & dosage
Phenotype
Polymorphism, Single Nucleotide
Pyridines--pharmacology
Pyrones--pharmacology
Ritonavir--pharmacology
Sulfonamides
Young Adult