Zhou, Delu Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase. [electronic resource] - Journal of leukocyte biology May 2010 - 845-55 p. digital Publication Type: Journal Article ISSN: 1938-3673 Standard No.: 10.1189/jlb.0409289 doi Subjects--Topical Terms: AnimalsCell SeparationEnzyme-Linked Immunosorbent AssayFlow CytometryImmunoprecipitationInterleukin-12 Subunit p40--biosynthesisMacrophages--immunologyMiceMice, Inbred C57BLMice, KnockoutPhosphatidylinositol 3-Kinases--immunologyProtein Tyrosine Phosphatase, Non-Receptor Type 6--immunologyReverse Transcriptase Polymerase Chain ReactionSignal Transduction--immunologyToll-Like Receptors--immunology