TY  - GEN
AU  - Zander,Serge A L
AU  - Kersbergen,Ariena
AU  - van der Burg,Eline
AU  - de Water,Niels
AU  - van Tellingen,Olaf
AU  - Gunnarsdottir,Sjöfn
AU  - Jaspers,Janneke E
AU  - Pajic,Marina
AU  - Nygren,Anders O H
AU  - Jonkers,Jos
AU  - Borst,Piet
AU  - Rottenberg,Sven
TI  - Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan
SN  - 1538-7445
PY  - 2010///0407
KW  - ATP Binding Cassette Transporter, Subfamily B
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - ATP Binding Cassette Transporter, Subfamily G, Member 2
KW  - ATP-Binding Cassette Transporters
KW  - genetics
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Carcinoma
KW  - drug therapy
KW  - Doxorubicin
KW  - therapeutic use
KW  - Drug Evaluation, Preclinical
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Inhibitors
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - drug effects
KW  - Genes, BRCA1
KW  - physiology
KW  - Genes, p53
KW  - Mammary Neoplasms, Animal
KW  - Maximum Tolerated Dose
KW  - Mice
KW  - Mice, Knockout
KW  - Phthalazines
KW  - pharmacology
KW  - Piperazines
KW  - Topoisomerase I Inhibitors
KW  - Topotecan
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1158/0008-5472.CAN-09-3367
ER  -