Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells. [electronic resource]
- Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie Jan 2011
- 167-73 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1618-1433
10.1016/j.etp.2009.11.005 doi
Anticarcinogenic Agents--pharmacology Blotting, Western Cell Proliferation--drug effects Cell Survival--drug effects Cyclin D1--biosynthesis Down-Regulation Flow Cytometry Hep G2 Cells Humans Liver--drug effects Liver Neoplasms--enzymology Microscopy, Confocal Proto-Oncogene Proteins c-akt--metabolism Resveratrol Signal Transduction Stilbenes--pharmacology p21-Activated Kinases--metabolism p38 Mitogen-Activated Protein Kinases--metabolism