TY - GEN AU - O'Sullivan,Roderick J AU - Karlseder,Jan TI - Telomeres: protecting chromosomes against genome instability SN - 1471-0080 PY - 2010///0423 KW - Base Sequence KW - DNA Damage KW - DNA Repair KW - Genomic Instability KW - Humans KW - Models, Biological KW - Repetitive Sequences, Nucleic Acid KW - genetics KW - Telomerase KW - metabolism KW - Telomere KW - Telomere-Binding Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1038/nrm2848 ER -