NGF-activated protein tyrosine phosphatase 1B mediates the phosphorylation and degradation of I-kappa-Balpha coupled to NF-kappa-B activation, thereby controlling dendrite morphology. [electronic resource]
- Molecular and cellular neurosciences Apr 2010
- 384-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1095-9327
10.1016/j.mcn.2010.01.005 doi
Animals Blotting, Western Cell Shape--drug effects Cells, Cultured Dendrites--drug effects Hippocampus--cytology I-kappa B Proteins--metabolism Immunohistochemistry Immunoprecipitation Mice NF-kappa B--metabolism Nerve Growth Factor--metabolism Phosphorylation--drug effects Protein Tyrosine Phosphatase, Non-Receptor Type 1--metabolism Receptor, Nerve Growth Factor--metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction--drug effects