TY  - GEN
AU  - Mahadeo,Kris M
AU  - Dhall,Girish
AU  - Panigrahy,Ashok
AU  - Lastra,Carlos
AU  - Ettinger,Lawrence J
TI  - Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury
SN  - 1521-0669
PY  - 2010///0426
KW  - Amino Acid Substitution
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Asparaginase
KW  - Child
KW  - Cytarabine
KW  - Daunorubicin
KW  - Endothelium, Vascular
KW  - drug effects
KW  - Epilepsy, Tonic-Clonic
KW  - chemically induced
KW  - Genetic Predisposition to Disease
KW  - Humans
KW  - Hyperhomocysteinemia
KW  - complications
KW  - Injections, Spinal
KW  - Leukoencephalopathies
KW  - Male
KW  - Methotrexate
KW  - administration & dosage
KW  - Methylenetetrahydrofolate Reductase (NADPH2)
KW  - genetics
KW  - Polymorphism, Single Nucleotide
KW  - Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Prednisone
KW  - Remission Induction
KW  - Sinus Thrombosis, Intracranial
KW  - Vincristine
N1  - Publication Type: Case Reports; Journal Article
UR  - https://doi.org/10.3109/08880010903341904
ER  -