TY  - GEN
AU  - Oelschlaeger,Peter
AU  - Ai,Ni
AU  - Duprez,Kevin T
AU  - Welsh,William J
AU  - Toney,Jeffrey H
TI  - Evolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm?
SN  - 1520-4804
PY  - 2010///0514
KW  - Algorithms
KW  - Anti-Bacterial Agents
KW  - chemistry
KW  - Bacterial Proteins
KW  - antagonists & inhibitors
KW  - Carbapenems
KW  - Crystallography, X-Ray
KW  - Databases, Factual
KW  - Drug Design
KW  - Drug Resistance, Multiple, Bacterial
KW  - Klebsiella pneumoniae
KW  - enzymology
KW  - Metalloproteins
KW  - Models, Molecular
KW  - Mutation
KW  - Protein Conformation
KW  - Substrate Specificity
KW  - beta-Lactamase Inhibitors
KW  - beta-Lactamases
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm9012938
ER  -