Torres, Mylin A <br/><br/>
AC480, formerly BMS-599626, a pan Her inhibitor, enhances radiosensitivity and radioresponse of head and neck squamous cell carcinoma cells in vitro and in vivo.  [electronic resource] 

 -  Investigational new drugs  Aug 2011 
 - 554-61 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1573-0646 
<br/><br/><label>Standard No.: </label>10.1007/s10637-010-9389-3  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Blotting, Western<br/>Carbamates--pharmacology<br/>Carcinoma, Squamous Cell--drug therapy<br/>Cell Count<br/>Cell Cycle--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>ErbB Receptors--metabolism<br/>Head and Neck Neoplasms--drug therapy<br/>Histones--metabolism<br/>Humans<br/>Immunoprecipitation<br/>Male<br/>Mice<br/>Mice, Nude<br/>Radiation Tolerance--drug effects<br/>Radiation, Ionizing<br/>Receptor, ErbB-2--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>Triazines--pharmacology<br/>Xenograft Model Antitumor Assays