TY - GEN AU - Ercan,D AU - Zejnullahu,K AU - Yonesaka,K AU - Xiao,Y AU - Capelletti,M AU - Rogers,A AU - Lifshits,E AU - Brown,A AU - Lee,C AU - Christensen,J G AU - Kwiatkowski,D J AU - Engelman,J A AU - Jänne,P A TI - Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor SN - 1476-5594 PY - 2010///0504 KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - ErbB Receptors KW - antagonists & inhibitors KW - Gefitinib KW - Gene Amplification KW - Humans KW - Lung Neoplasms KW - Phosphorylation KW - Protein Kinase Inhibitors KW - pharmacology KW - Quinazolines KW - Quinazolinones N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2009.526 ER -