TY - GEN AU - Moreno-Rubio,Juan AU - Herrero-Beaumont,Gabriel AU - Tardio,Lidia AU - Alvarez-Soria,M Angeles AU - Largo,Raquel TI - Nonsteroidal antiinflammatory drugs and prostaglandin E(2) modulate the synthesis of osteoprotegerin and RANKL in the cartilage of patients with severe knee osteoarthritis SN - 0004-3591 PY - 2010///0329 KW - Aged KW - Aged, 80 and over KW - Anti-Inflammatory Agents, Non-Steroidal KW - therapeutic use KW - Celecoxib KW - Cells, Cultured KW - Chondrocytes KW - cytology KW - Cyclooxygenase 2 Inhibitors KW - Dinoprostone KW - metabolism KW - Dose-Response Relationship, Drug KW - Gene Expression KW - drug effects KW - Humans KW - Immunohistochemistry KW - Osteoarthritis, Knee KW - drug therapy KW - Osteoprotegerin KW - genetics KW - Pyrazoles KW - RANK Ligand KW - Receptors, Prostaglandin E KW - agonists KW - Severity of Illness Index KW - Signal Transduction KW - Sulfonamides N1 - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/art.27204 ER -