TY - GEN AU - Huang,Chi-Chang AU - Lo,Chiu-Ping AU - Chiu,Chih-Yang AU - Shyur,Lie-Fen TI - Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in mice SN - 1476-5381 PY - 2010///0709 KW - Adenocarcinoma KW - blood supply KW - Animals KW - Anticarcinogenic Agents KW - pharmacology KW - Antineoplastic Agents, Phytogenic KW - Antioxidants KW - Apoptosis KW - drug effects KW - Breast Neoplasms KW - Caspases KW - metabolism KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Movement KW - Cell Proliferation KW - Cyclin-Dependent Kinase Inhibitor p21 KW - Cyclooxygenase 2 KW - Dose-Response Relationship, Drug KW - Female KW - Humans KW - JNK Mitogen-Activated Protein Kinases KW - Lactones KW - Lung Neoplasms KW - Matrix Metalloproteinase 9 KW - Mice KW - Mice, Inbred BALB C KW - NF-kappa B KW - Neoplasm Invasiveness KW - Paclitaxel KW - Reactive Oxygen Species KW - Sesquiterpenes KW - Time Factors KW - Tumor Burden KW - Tumor Necrosis Factor-alpha KW - Vascular Endothelial Growth Factor A KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1476-5381.2009.00581.x ER -