TY  - GEN
AU  - Li,Feng
AU  - Wang,Laiyou
AU  - Guo,Grace L
AU  - Ma,Xiaochao
TI  - Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice
SN  - 1521-009X
PY  - 2010///0917
KW  - Animal Structures
KW  - metabolism
KW  - Animals
KW  - Anti-HIV Agents
KW  - blood
KW  - Aryl Hydrocarbon Hydroxylases
KW  - antagonists & inhibitors
KW  - Biocatalysis
KW  - drug effects
KW  - Chromatography, High Pressure Liquid
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2D6
KW  - genetics
KW  - Cytochrome P-450 CYP2D6 Inhibitors
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Dealkylation
KW  - Drug Interactions
KW  - Feces
KW  - chemistry
KW  - Humans
KW  - Hydroxylation
KW  - Metabolomics
KW  - methods
KW  - Mice
KW  - Mice, Inbred Strains
KW  - Microsomes, Liver
KW  - Molecular Structure
KW  - Oxidation-Reduction
KW  - Principal Component Analysis
KW  - Pyridines
KW  - Pyrones
KW  - Recombinant Proteins
KW  - Ritonavir
KW  - pharmacology
KW  - Spectrometry, Mass, Electrospray Ionization
KW  - Sulfonamides
KW  - Tissue Distribution
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1124/dmd.109.030817
ER  -