TY - GEN AU - Stein,Rhona AU - Gupta,Pankaj AU - Chen,Xiaochuan AU - Cardillo,Thomas M AU - Furman,Richard R AU - Chen,Susan AU - Chang,Chien-Hsing AU - Goldenberg,David M TI - Therapy of B-cell malignancies by anti-HLA-DR humanized monoclonal antibody, IMMU-114, is mediated through hyperactivation of ERK and JNK MAP kinase signaling pathways SN - 1528-0020 PY - 2010///0709 KW - Animals KW - Antibodies, Monoclonal KW - immunology KW - Antigens, CD KW - B-Lymphocytes KW - Cell Line, Tumor KW - Cytotoxins KW - Drug Screening Assays, Antitumor KW - Enzyme Activation KW - drug effects KW - Extracellular Signal-Regulated MAP Kinases KW - Female KW - HLA-DR Antigens KW - Hematologic Neoplasms KW - drug therapy KW - Humans KW - MAP Kinase Kinase 4 KW - MAP Kinase Signaling System KW - Mice KW - Mice, SCID N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2009-06-228288 ER -